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Saturday, March 10, 2012

Mobile Phone Use and Cancer: Searching for Answers | Biomedical ...

It is maybe the most controversial scientific question of the last ten years. Does mobile phone use cause cancer? You would feel with all the research studies performed on this subject in the last decade this question has long been answered but the answer is not a basic “yes” or “no.”

The source of the concerns are the so-called electromagnetic fields (EMF). Every day, we are exposed to two sorts of EMF, namely (1) really low frequency electromagnetic fields (ELF) which come from electronic appliances and power lines and (2) radiofrequency radiation (RF) which comes from wireless devices such as cell phones and cordless phones, base stations, antennas, and broadcast transmission towers.

Most of the investigation studies on the issue of RF exposure had been conducted in the framework of the INTERPHONE study, a multi-country series of case-controlled studies. The countries involved were Australia, Canada, Denmark, Finland, France, Germany, Israel, Italy, Japan, New Zealand, Norway, Sweden, and the UK. The studies looked at the associations between mobile phone use and the incidence of brain tumors such as glioma, meningioma, acoustic neuroma and cancer of the parotid gland. The Interphone studies had been funded and supported by numerous international and governmental agencies as properly as market groups like the Global System for Mobile communications Association (GSMA) and the Mobile Manufacturers Forum (MMF). Numerous independent studies have also been also performed.

Let’s take a look at the two sides of the coin.

THOSE WHO SAY NO

The majority of articles published throughout the last decade report that no association was observed between mobile phone use and increased cancer risk and as a result numerous organizations say that there is no sufficient scientific evidence to prove that prolonged RF exposure from mobile phones can trigger cancer.

(1) According to the Institute of Cancer Epidemiology in Denmark, a study involving 420,000 Danish mobile phone users did not identify an increased risk for cancer. This is the largest published study so far on the health effects of mobile phone use.

(2) In laboratory studies involving rats and mice (in vivo studies), exposure to wireless communication signals did not significantly enhance the incidence of tumors.

(3) In vitro studies showed no induction of cell transformation by low-level RF radiation.

(four) The French INTERPHONE study did not locate significant increased risk for meningioma or neuroma in mobile phone users. Neither did the German and the British studies.

(5) In a big US study involving over 12,000 participants, no overall increased risk for brain tumors were discovered about mobile phone users.

(6) The US National Cancer Institute says the majority of studies conducted on this subject do not show any association between mobile phone use and cancer.

(7) The World Wellness Organization (WHO) says that existing scientific evidence indicates that exposure to RF fields, such as those emitted by mobile phones and their base stations, is unlikely to induce or promote cancers.

(8) Cancer Study UK says that radiation coming from phone handsets and base stations are too low to cause harm to human DNA and trigger cancer.

THOSE WHO SAY YES

Numerous consumer groups are wary of the outcomes of the INTERPHONE studies since of the phone industry’s strong role in the funding. The involvement of GSMA and MMF is not unusual. Market-funded research is quite typical in biomedical science. Sadly, there have been recent controversies concerning conflicts of interest on the part of scientists who acquire funding from the pharmaceutical industry. These incidents sadly put a question mark on the integrity of several scientific studies that are valid and bona fide, regardless of sources of funding.

There are also groups and people who are convinced of the hazards of EMF. Contrary to common belief that only lay people and consumer groups think in the mobile phone-cancer link, several scientists are in fact taking a second look at the evidence at hand.

(1) An international working group of scientists formed the BioInitiative Working Group and prepared a report that raises serious concerns about the safety of existing public limits that regulate how much EMF is allowable from power lines, cell phones, and several other sources of EMF exposure in every day life. The BioInitiative Report looked at evidence from published and unpublished information on the links between EMF exposure and immune disorders, anxiety response, neurological and behavioural issues and even studies on childhood cancers (e.g. leukemia) and breast cancer. One of their conclusions is that there is little doubt that exposure to ELF causes childhood leukemia. In addition, the report also found that the current safety standards for exposure to EMF from cell phones and other handsets are not safe at all. As supporting evidence, they cited studies reporting lengthy-term brain tumor and acoustic neuroma risks.

The BioInitaive Report also discovered ELF exposure to be a risk factor for breast cancer and possibly other cancers as properly. The Working Group is clearly demanding a re-examination of the safety standards of the telecommunications business. Even so, the report does not clearly define the group’s stand about RF and cancer.

(2) The International Agency for Cancer Analysis classifies ELF as a possible human carcinogen.

(3) In the case of RF, Swedish researchers led by L. Hardell found increased risk for brain tumors among 2,162 users of cordless handsets and cellular phones. These researchers had been the only ones who discovered these associations in analysing information from the INTERPHONE studies. They also looked at associations with risks for other kinds of cancer such as testicular cancer and non-Hodgkin’s lymphoma with inconclusive outcomes.

(four) Yet another group of Swedish researchers looked at the incidence of acoustic neuroma in a group of 752 men and women. Their findings did not show a link between short-term mobile phone use and increased risk for acoustic neuroma. Even so, a link was observed when taking lengthy-term phone use (e.g. at least 10 years) into consideration.

(5) In 2000, a class action suit was filed against Verizon, Motorola and other wireless organizations led by former employees who developed brain tumors. So far, no damages have been awarded.

(6) In early 2008, Israeli researchers discovered a positive dose-response trend between cell phone use and parotid gland tumors in a study that looked at 1,266 people.

(7) The head of the University of Pittsburgh Cancer Institute, Dr. Ronald Herberman issued a memo in July 2008 warning the institute’s staff against their children’s use of mobile phones. He based his concerns on unpublished information and the truth that ” it takes too lengthy to get answers from science…people ought to take action now.

(8) A study by Finnish researchers published in 2008 showed that RF-EMF can alter protein expression in human skin cells. This is the first study to report that RF-EMF can trigger adjustments at the molecular level.

THERE ARE A lot of Factors WHY A CLEAR-CUT ANSWER TO THE QUESTION REMAINS ELUSIVE.

(1) Sample size. Studies with tiny sample sizes lack statistical power. A lot of studies published have too tiny sample sizes to have convincing results.

(2) Study designs. Study designs are tough to standardize, making pooling of study outcomes also challenging.

(three) Information collection. Data on exposure is mostly based on self-reports of phone use. Unfortunately, these recalls are often inaccurate. It has been observed, for example, that individuals tend to underestimate the number of calls but overestimate the duration of calls they make.

(4) Exposure. There numerous sources of EMFs around us. Radiation might come from cellular phones, hand-held phones, cordless handsets, base stations, and telecom masts. Other household appliances including microwave ovens also emit radiation. It is very challenging to uncover unexposed study participants which can be utilised as study controls.

(5) Time. Studying the well being effects of phone use takes time. Prospective studies are still more dependable that retrospective studies but they take longer to total. A Swedish study discovered an increased risk of acoustic neuroma only after at least 10 years of phone use. Most short-term studies came up with negative outcomes.

(6) Lack of data. Most RF exposure information obtainable are on adult phone users. Extremely limited RF exposure data on children are available. The hypothesis that kids and adolescents as developing organisms with developing organs are particularly vulnerable can not be tested at this point in time.

WHAT DO WE DO NOW?

In circumstances such as this when there is a high degree of scientific uncertainty, the World Health Organization recommends following the policies of precautionary principle, prudent avoidance, and ALARA (As Low As Reasonably Achievable). These cautionary policies had been released in March 2000. It’s been much more than 8 years and the policies remain the identical. Many countries in Europe recommend comparable policies.

The suggested use of hands-totally free technologies by the US FDA and other well being agencies works much more for safety when phoning even though driving but does not really address the safety issue of RF. Consumer groups have been demanding for years that phone makers install radiation blocking devices on their handsets. So far, their demands have remained unheeded.

Let’s hope that science comes up with the answer soon. In the meantime, it’s up to us to make the decisions concerning mobile phone use for ourselves and our families.

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